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sexta-feira, 15 dezembro 2017 16:01

Systematic overview of neuroanatomical differences in ADHD: Definitive evidence

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Bruno Bastos Vieira de Melo1, Maria João Trigueiro2, Pedro Pereira Rodrigues3

1
Occupational Therapy Department, Higher School of Health, Polytechnic Institute of Porto, Porto, Portugal; Faculty of Education Sciences, University of Vigo
2
Occupational Therapy Department, Higher School of Health, Polytechnic Institute of Porto, Porto, Portugal
3
CINTESIS & Community Medicine, Information and Health Decision Sciences Department, Faculty of Medicine, University of Porto, Porto, Portugal

Taylor & Francis Online

15 Dec 2017


Abstract:

Objectives:This article seeks to identify neuroanatomical differences in ADHD through an overview of systematic reviews that report encephalic differences compared to a control group in volume, area, activation likelihood or chemical composition.

Method:We conducted a systematic search using Cochrane guidelines and PRISMA criteria in PubMed, Scopus, Web of Science, Cochrane Database of Systematic Reviews and Database of Abstracts of Reviews of Effects.

Results:Results revealed broad encephalic involvement that includes a functional frontal and cingulate hypoactivation and structural differences in corpus callosum, cerebellum and basal nuclei.

Conclusions: ADHD symptoms might be due to a multi-network unbalanced functioning hypothesis.


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