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Artigos Científicos

segunda-feira, 29 outubro 2018 14:13

Methylphenidate and Reduced Overweight in Children With ADHD

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Elisabeth Mellström1,2, Cecilia Forsman3, Lisbet Engh4Maria Unenge Hallerbäck4,5Sverre Wikström3

Karlstad Central Hospital, Sweden
Queen Silvia Children’s Hospital, Gothenburg, Sweden
Örebro University, Sweden
Karlstad University, Sweden
University of Gothenburg, Sweden

Journal of Attention Disorders: SAGE Journals

October 4, 2016


Objective: The objective of this study was to investigate odds ratios of overweight/obesity in children with ADHD and to compare the change in body mass index (BMI) after initiation of methylphenidate treatment in normal versus overweight/obese children.

Method: This population-based study included 724 children (<18 years), of whom 197 were girls. Odds ratios for overweight and obesity were calculated, comparing the study group with a reference group from the same area. After initiation of methylphenidate treatment, changes in BMI were assessed for up to 3 years.

Results: Children with ADHD had an odds ratio of 1.87 (95% confidence interval [CI]: [1.60, 2.19]) for overweight/obesity. A decrease in BMI standard deviation score was identified 1 to 3 years into treatment. The decrease was beneficially greater in overweight/obese as compared with normal weight children-mean (SD) −0.64 (0.80) versus −0.39 (0.68); p = .001-and greater in girls.

Conclusion: Medication with methylphenidate may facilitate favorable weight development in children with ADHD and overweight/obesity.

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