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Investigação em PHDA

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Medication treatment for attention‐deficit/hyperactivity disorder and the risk of acute seizures in individuals with epilepsy

Maria Grazia Melegari1,Stefania Sette1Elena Vittori2Luca Mallia3Alessandra Devoto1Fabio Lucidi1Raffaele Ferri4Oliviero Bruni1

Sapienza University, Rome, Italy
Centro Ricerca e Cura Balbuzie e disturbi della voce e del linguaggio, Rome, Italy
University of Rome “Foro Italico,” Italy
Oasi Institute (Istituto di Ricovero e Cura a carattere scientifico), Troina, Italy

Journal of Attention Disorders: SAGE Journals

February 22, 2018


Objective: The objective of this study was to assess the links between temperament and sleep in a group of preschoolers with ADHD.

Method: Twenty-five ADHD (M = 5.37 years, SD = 1.09) and 22 typically developing (TD; M = 5.10, SD = 1.18) preschoolers participated in the study. Sleep was assessed with the Sleep Disturbance Scale and wrist actigraphy. The Preschool Temperament and Character Inventory (PsTCI) was used to evaluate the child temperament.

Results: ADHD children showed a temperamental profile characterized by higher novelty seeking, lower persistence, self-directness, and cooperativeness and marginally lower harm avoidance (HA) compared with controls. HA was associated negatively to wakefulness after sleep onset and sleep fragmentation and positively with sleep efficiency and sleep time. Reward dependence was negatively associated with wake episode length.

Conclusion: Sleep and temperament are correlated in preschoolers with ADHD and temperament might represent an intermediate endophenotype underlying the relation between ADHD and sleep disorders

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A Direção da SPDA - Sociedade Portuguesa de Défice de Atenção